tag:blogger.com,1999:blog-7447544468792389936.post664101730039465897..comments2024-02-26T21:18:23.165-08:00Comments on CHIMERAS: Of hierarchies, mice, and neuronsAnonymoushttp://www.blogger.com/profile/09922888671399516573noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-7447544468792389936.post-27002584786461856212011-11-21T10:49:49.010-08:002011-11-21T10:49:49.010-08:00You can play it in many different ways. The tricky...You can play it in many different ways. The tricky part is that the brain has its own immune system, the building blocks of which are made of cells called "microglia." You'd definitely need a vaccine to protect from the virus, but depending on where you inject the virus it can be a tricky affair. Suppose the vaccine stimulates an antibody response, but then you inject the virus through the ear, and the virus quickly moves to the brain... I confess I don't know much about it. The questions that come to mind are: (1) is an antibody vaccine enough to stimulate a microglia response in the brain? (2) can a vaccine stimulate a microglia response?<br /><br />I'll try and see if I can find some more info on this, sounds like a fascinating question in general!Anonymoushttps://www.blogger.com/profile/09922888671399516573noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-66419040237517441702011-11-21T10:32:28.124-08:002011-11-21T10:32:28.124-08:00Definitely! Just have to finish it :-)
On that no...Definitely! Just have to finish it :-)<br /><br />On that note, if someone, at a hopefully not too near future time, were to develop a "targeted viral behavior modifier" what kinds of defense would be useful. (Hand waving is fine.) For example:<br />1) Some sort of anti-viral immune system response to recognize this sort of manufactured virus.<br />2) Some sort of nano-tech totally new "immune system" <br />3) ...Steve Halterhttps://www.blogger.com/profile/03160423930602205230noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-1245272725124056432011-11-21T08:42:40.447-08:002011-11-21T08:42:40.447-08:00...of course, I _expect_ to be mentioned in the ac......of course, I _expect_ to be mentioned in the acknowledgments when the book comes out!!! ;-)Anonymoushttps://www.blogger.com/profile/09922888671399516573noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-1927086344340057902011-11-21T08:21:34.289-08:002011-11-21T08:21:34.289-08:00Cool! Let me know how it works out!Cool! Let me know how it works out!Anonymoushttps://www.blogger.com/profile/09922888671399516573noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-89221251580975222572011-11-21T08:19:17.982-08:002011-11-21T08:19:17.982-08:00This actually fits in with part of the story I'...This actually fits in with part of the story I'm working on. I may have to revise my estimate of when this sort of thing could be done.Steve Halterhttps://www.blogger.com/profile/03160423930602205230noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-83403014021090683322011-11-21T07:11:45.541-08:002011-11-21T07:11:45.541-08:00Hmmm. I hadn't thought of that. Could make a d...Hmmm. I hadn't thought of that. Could make a deliciously nasty thriller... ;-)Anonymoushttps://www.blogger.com/profile/09922888671399516573noreply@blogger.comtag:blogger.com,1999:blog-7447544468792389936.post-34448926397518419062011-11-21T06:46:29.965-08:002011-11-21T06:46:29.965-08:00Altering behavior through a viral modified pyramid...Altering behavior through a viral modified pyramidal neuron DNA--now that has some scary implications.Steve Halterhttps://www.blogger.com/profile/03160423930602205230noreply@blogger.com